The Relationship Between Sleep, Fatigue and Quality of Life in Young Adults With Autoimmune Addison′s Disease

Non-restorative sleep emerged as a distinct feature of AAD. While the prevalence and severity of sleep impairments were similar to controls, the association with poorer physical health was stronger in patients. Mental health remained similar despite sleep disturbances. These findings highlight the importance of addressing even modest sleep disturbances, which may worsen fatigue and reduce physical wellbeing in AAD.

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Publication Details

Journal
Clinical Endocrinology
Published
2025-09-02
DOI
https://doi.org/10.1111/cen.70028
Primary Topic
Adrenal Hormones and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

The Relationship Between Sleep, Fatigue and Quality of Life in Young Adults With Autoimmune Addison′s Disease

Tim Spelman, Annelies van’t Westeinde, Svetlana Lajić, Sophie Bensing et al.
Clinical Endocrinology
Adrenal Hormones and Disorders
article

The Relationship Between Sleep, Fatigue and Quality of Life in Young Adults With Autoimmune Addison′s Disease

Tim Spelman, Annelies van’t Westeinde, Svetlana Lajić, Sophie Bensing, Sara Fletcher‐Sandersjöö, Tatja Hirvikosi
article en

Abstract

Non-restorative sleep emerged as a distinct feature of AAD. While the prevalence and severity of sleep impairments were similar to controls, the association with poorer physical health was stronger in patients. Mental health remained similar despite sleep disturbances. These findings highlight the importance of addressing even modest sleep disturbances, which may worsen fatigue and reduce physical wellbeing in AAD.

Clinical EndocrinologyVol. 103(6)
Karolinska University Hospital (SE), Peter MacCallum Cancer Centre (AU), Sahlgrenska University Hospital (SE), Karolinska Institutet (SE), Stockholm Health Care Services (SE), The University of Adelaide (AU), University of Gothenburg (SE)
Karolinska Institutet, Stockholms Läns Landsting, Vetenskapsrådet, Stiftelsen Sven Jerrings Fond, Lisa och Johan Grönbergs Stiftelse, Stiftelsen Samariten, Wera Ekströms Stiftelse för Pediatrisk Forskning, Marcus och Amalia Wallenbergs minnesfond, Sällskapet Barnavård
Openalex Percentile: Top 68%
Adrenal Hormones and Disorders
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The Relationship Between Sleep, Fatigue and Quality of Life in Young Adults With Autoimmune Addison′s Disease — Tim Spelman, Annelies van’t Westeinde, et al. · Clinical Endocrinology (2025) | TGRS Research Map | TGRS