Toward Semiautomated Analysis of Cerebrovascular Reserve: Enhancing Objective Comparisons Using 99mTc-HMPAO SPECT With Acetazolamide in Moyamoya
Although 99m Tc-HMPAO remains a validated modality for CVR assessment, its interpretation is operator-dependent. The proposed semiautomated method offers high specificity and greater objectivity, supporting its integration into clinical workflows. Further multicenter validation is warranted.
Authors
- Gauthier Delaby (ORCID: https://orcid.org/0000-0003-4324-9095)
- Hilde Hénon (ORCID: https://orcid.org/0000-0001-6274-7562)
- Renaud Lopes (ORCID: https://orcid.org/0000-0002-2425-2283)
- Rabih Aboukaïs (ORCID: https://orcid.org/0000-0002-2212-806X)
- Antoine Rogeau (ORCID: https://orcid.org/0000-0002-3993-3954)
- Nadira Delhem (ORCID: https://orcid.org/0000-0003-1528-2357)
- Martin Bretzner (ORCID: https://orcid.org/0000-0002-7594-4159)
- Cécile Bordier (ORCID: https://orcid.org/0000-0003-2376-5922)
- Antoine Devalckeneer (ORCID: https://orcid.org/0000-0002-6111-3768)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Lille (FR)
- Institut Pasteur de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Lille’s Cardiology Hospital (FR)
- Onco Lille (FR)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1227/neu.0000000000003716
- Primary Topic
- Moyamoya disease diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Institut National de la Santé et de la Recherche Médicale