Optimizing Early Ophthalmology Clinical Trials: Home OCT and Modeling Can Reduce Sample Size by 20% to 40%

By reducing sample size requirements while maintaining statistical power, this approach can streamline clinical trials, expediting the development of new retinal therapies and improving patient access to treatment.

Authors

Bernhard Steiert (ORCID: https://orcid.org/0000-0002-1398-1624)
Jacques Hermes (ORCID: https://orcid.org/0000-0003-3608-5969)

Institutions

Roche (Switzerland) (CH)
University of Freiburg (DE)

Publication Details

Journal: Translational Vision Science & Technology
Published: 2025-09-02
DOI: https://doi.org/10.1167/tvst.14.9.2
Citations: 1
Primary Topic: Retinal Imaging and Analysis
Type: article
Field-Weighted Citation Impact: 1.36

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OCT

article

Optimizing Early Ophthalmology Clinical Trials: Home OCT and Modeling Can Reduce Sample Size by 20% to 40%

Bernhard Steiert, Jacques Hermes

Sep 2, 2025

1 citations

Translational Vision Science & Technology

Retinal Imaging and Analysis

1.36

article

Optimizing Early Ophthalmology Clinical Trials: Home OCT and Modeling Can Reduce Sample Size by 20% to 40%

Bernhard Steiert, Jacques Hermes

September 2, 2025article en

1 citations

Abstract

Translational Vision Science & TechnologyVol. 14(9)

Roche (Switzerland) (CH), University of Freiburg (DE)

Openalex Percentile: Top 16%

Retinal Imaging and Analysis

1.36

DOI Open Access PDF OpenAlex

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Optimizing Early Ophthalmology Clinical Trials: Home OCT and Modeling Can Reduce Sample Size by 20% to 40% — Bernhard Steiert, Jacques Hermes · Translational Vision Science & Technology (2025) | TGRS Research Map | TGRS