Nkx3.2 Inhibits Retinal Degeneration by Modulating Inflammation and Cell Death in RPE
Nkx3.2 can suppress inflammatory responses and necroptic cell death in RPE. By employing these mechanisms, Nkx3.2 may play a significant role in inhibiting retinal degeneration caused by aging and oxidative stress.
Authors
- Minsun Park (ORCID: https://orcid.org/0000-0002-4016-8567)
- Yun Seob Song (ORCID: https://orcid.org/0000-0002-0909-3341)
- Hyunjin Jeong (ORCID: https://orcid.org/0000-0003-4386-3845)
- Hae-Sol Shin
- Nari Ryu
- Ji‐Yeon Han (ORCID: https://orcid.org/0000-0003-3780-358X)
- Kyoung Yul Seo (ORCID: https://orcid.org/0000-0002-9855-1980)
- Seung Won Choi (ORCID: https://orcid.org/0000-0003-1203-6126)
- Sanghyuk Lee (ORCID: https://orcid.org/0000-0001-9230-7461)
- Dae Won Kim (ORCID: https://orcid.org/0000-0001-8785-4508)
- Daun Jeong (ORCID: https://orcid.org/0000-0003-0769-9697)
- Hye-Kyoung Oh
- Jun-Ho Jang (ORCID: https://orcid.org/0000-0003-0038-2435)
Institutions
- Ewha Womans University (KR)
- Yonsei University (KR)
- Severance Hospital (KR)
- Korea Pharma (South Korea) (KR)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1167/iovs.66.12.2
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Korea Drug Development Fund
- Ministry of Science and ICT, South Korea