MR‐ARFI to evaluate intensity variability and enhance targeting of FUS: A brain study in rats
Despite initial MRI guidance, substantial targeting errors were observed, highlighting the need for advanced imaging techniques like MR-ARFI in neuromodulation procedures. Moreover, ARFI displacements in the target region across subjects varied over three-fold, indicating very high variation in the delivered acoustic pressure. By improving the precision of FUS targeting and estimating deviations in the FUS pressure, MR-ARFI can improve therapeutic outcomes and reduce risks in transcranial FUS neuromodulation.
Authors
- Eric P. Cunningham (ORCID: https://orcid.org/0000-0002-8683-0923)
- Kim Butts Pauly (ORCID: https://orcid.org/0000-0002-6281-2771)
- Donna J. Calu (ORCID: https://orcid.org/0000-0003-2377-9494)
- David Martin (ORCID: https://orcid.org/0000-0003-2223-621X)
- Linda Chang (ORCID: https://orcid.org/0000-0002-1267-0699)
- Abubakr Eldirdiri (ORCID: https://orcid.org/0000-0002-3879-3881)
- Stephanie Bernard (ORCID: https://orcid.org/0000-0002-8410-2295)
- Thomas Ernst (ORCID: https://orcid.org/0000-0003-1211-7655)
Institutions
- University of Maryland, Baltimore (US)
- Stanford University (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1002/mrm.70039
- Citations
- 2
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Focused Ultrasound Foundation