Could a Preservative Have Prevented the Extremely-Drug Resistant <i>Pseudomonas aeruginosa</i> Artificial Tears Associated Eye Infection Outbreak of 2023?
Several common preservatives were effective in eliminating PA strains including the outbreak strain CDC1270. Preservative efficacy was delayed or inhibited in rich media (MHB) compared to PBS. These results suggest that the 2023 outbreak could have been prevented by using a common preservative in the artificial tears.
Authors
- Michael E. Zegans (ORCID: https://orcid.org/0000-0003-3074-7589)
- Robert M. Q. Shanks (ORCID: https://orcid.org/0000-0002-7699-5396)
- Eric G. Romanowski (ORCID: https://orcid.org/0000-0003-4246-3276)
Institutions
- Dartmouth College (US)
- UPMC Health System (US)
Publication Details
- Journal
- Current Eye Research
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1080/02713683.2025.2553642
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eye and Ear Foundation of Pittsburgh
- Research to Prevent Blindness
- National Institutes of Health