Reverse Regulation of Th1 and Treg Immune Responses by P2X7 Receptor: A Possible Cause of the Progression of Experimental Autoimmune Uveitis
Our findings indicate that the promoting role of P2X7R in the early pathogenesis of EAU may be related to the contrary regulation of Th1 cells and Tregs, providing a new theoretical basis for the development of P2X7R targeted therapy.
Authors
- Xiaoxiang Peng (ORCID: https://orcid.org/0000-0001-6339-0462)
- Ronglan Zhao (ORCID: https://orcid.org/0000-0002-4302-2563)
- Yanan Du (ORCID: https://orcid.org/0000-0003-2627-9727)
- Shuping Luo
- Yahui Cao
Institutions
- Yuhuangding Hospital (CN)
Publication Details
- Journal
- Current Eye Research
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1080/02713683.2025.2553644
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province