Epigenetic landscape of IL-10 in Graves’ disease: site-specific DNA methylation alterations and their associations with immune dysregulation
Our findings highlight distinct methylation patterns of the IL-10 gene in GD, with specific CpG sites carrying potential implications for disease diagnosis, stratification, and monitoring.
Authors
- Kun Mu (ORCID: https://orcid.org/0000-0002-1955-5802)
- Jin‐an Zhang (ORCID: https://orcid.org/0000-0002-1700-4695)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-7346-555X)
- Na Li (ORCID: https://orcid.org/0000-0003-1056-3264)
- Yalin Wang (ORCID: https://orcid.org/0000-0002-6241-735X)
- Guangxin Li (ORCID: https://orcid.org/0000-0003-2524-0556)
- Wenyu Xu
- Yangping Yang
Institutions
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Expert Review of Clinical Immunology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1080/1744666x.2025.2554656
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China