Association between metabolites and hepatocellular carcinoma: findings from a two-sample Mendelian randomization study
This comprehensive MR study identified several metabolites with potential causal roles in HCC development. Our findings highlight nutrient transport, lipid metabolism, and related regulatory mechanisms as key components of HCC pathogenesis, offering new avenues for biomarker discovery and therapeutic intervention.
Authors
- Bao Le Thai Tran (ORCID: https://orcid.org/0009-0007-9387-7352)
- Tho Thi Anh Tran (ORCID: https://orcid.org/0000-0002-4712-257X)
- Van Mai Truong (ORCID: https://orcid.org/0000-0002-1473-9485)
- Nuyun Cao (ORCID: https://orcid.org/0009-0002-9792-9926)
- Tung Hoang (ORCID: https://orcid.org/0000-0001-6653-3406)
Institutions
- Vietnam National University Ho Chi Minh City (VN)
- Hanoi Medical University (VN)
- Khanh Hoa General Hospital (VN)
Publication Details
- Journal
- Journal of Liver Cancer
- Published
- 2025-09-02
- DOI
- https://doi.org/10.17998/jlc.2025.08.26
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tập đoàn Vingroup - Công ty CP
- Viet Nam National University Ho Chi Minh City
- Quỹ Đổi mới sáng tạo Vingroup