In-depth evaluation of XPR1 as a new prognostic indicator for endometrial cancer

This study identified a significant association between elevated XPR1 expression and adverse clinical outcomes in endometrial carcinoma patients, with additional connections observed to m6A modification and tumor immune microenvironment dynamics. As a novel prognostic indicator, XPR1 demonstrated correlations with tumor aggressiveness features and biological processes-including cellular proliferation, invasion, and m6A/immune-related pathways-suggesting its potential biological relevance in endometrial carcinogenesis. However, its independent prognostic value remains undefined, and direct mechanistic roles in m6A-mediated post-transcriptional modulation warrant subsequent experimental validation.