CYP2D6 UM phenotype is not related to suicide attempts in depressive patients in secondary psychiatric care
Based on our results, CYP2D6 UMs are not over-represented among suicide attempters in depressed patients treated in secondary psychiatric care. Analysis of CYP2D6 genotype can be useful for optimizing pharmacological treatment in depression but genotyping does not seem relevant for the clinical assessment of suicidality in difficult-to-treat depression.
Authors
- Amanda Holck
- Henrik Gréen (ORCID: https://orcid.org/0000-0002-8015-5728)
- Åsa Westrin (ORCID: https://orcid.org/0000-0003-3429-8418)
- Margareta Reis (ORCID: https://orcid.org/0000-0002-6041-0744)
- Marie Asp (ORCID: https://orcid.org/0000-0002-4897-1055)
Institutions
- Linköping University (SE)
- Lund University (SE)
- Swedish National Board of Forensic Medicine (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Nordic Journal of Psychiatry
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1080/08039488.2025.2553573
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Rättsmedicinalverket