Synthesis and Biological Study of S-triazines from Chalcones

A series of novel S-triazine derivatives were synthesized through a multi-step reaction. The process began with the reaction of cyanuric chloride and p-methoxyphenol, followed by interaction with 1-(5-hydroxyphenyl) ethenone and various aldehydes to form chalcone intermediates. These chalcones were then reacted with 2-aminobenzimidazole to yield the desired S-triazine derivatives. Characterization of all prepared compounds are done using spectroscopic method which includes proton NMR, carbon-13 NMR, Infrared and Mass spectroscopy. All prepared compounds were screened for their antibacterial activity against gram positive and gram negative bacteria.