Monitoring Treatment Response in Rectal Cancer through Circulating Tumor Cell Dynamics: A Pilot Clinical Study
This pilot study highlights the clinical relevance of CTC monitoring in rectal cancer. CTC dynamics appear to reflect treatment efficacy and may serve as an early indicator of response. These findings support the development of a randomized clinical trial comparing rectal cancer treatments with and without neoadjuvant therapy, using CTC trends as a primary outcome measure.
Authors
- Monika Vidlařová
- Lucia Ihnát Rudinská (ORCID: https://orcid.org/0000-0002-4938-7723)
- Eva Skácelíková
- Josef Srovnal (ORCID: https://orcid.org/0000-0003-1063-8334)
- Peter Ihnát (ORCID: https://orcid.org/0000-0001-6353-6257)
- Pavel Stejskal (ORCID: https://orcid.org/0000-0003-2593-2210)
- Ádám Varga (ORCID: https://orcid.org/0009-0009-2898-2396)
- Branislav Šnajder
Institutions
- University Hospital Ostrava (CZ)
- Institute of Molecular and Translational Medicine (CZ)
- Palacký University Olomouc (CZ)
Publication Details
- Journal
- Journal of Surgical Oncology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1002/jso.70073
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00