Temporal Variation of Biochemical Markers and Adenoma Predictors in Normocalcemic Primary Hyperparathyroidism: A Multicenter Retrospective Analysis
The large scale of our patient cohort reinforces the robustness of our statistical analyses and provides comprehensive insight into the dynamic nature of nPHPT. Our findings demonstrate that, even in normocalcemic patients, higher PTH levels and relatively higher calcium levels within the normal range are important indicators of parathyroid adenoma. Integrating serial biochemical measurements with targeted imaging can facilitate earlier diagnosis, potentially preventing future complications and informing more tailored management strategies.
Authors
- Nurdan Gül (ORCID: https://orcid.org/0000-0002-1187-944X)
- Berçem Ayçiçek (ORCID: https://orcid.org/0000-0001-7085-5846)
- Mazhar Müslüm Tuna (ORCID: https://orcid.org/0000-0001-5975-7786)
- Neşe Ersöz Gülçelik (ORCID: https://orcid.org/0000-0001-8212-5752)
- Ersen Karakılıç (ORCID: https://orcid.org/0000-0003-3590-2656)
- Bekir Uçan (ORCID: https://orcid.org/0000-0002-0810-5224)
- Gülhan Akbaba (ORCID: https://orcid.org/0000-0001-5849-0071)
- Murat Çalapkulu (ORCID: https://orcid.org/0000-0002-7445-2275)
- Güven Barış Cansu (ORCID: https://orcid.org/0000-0003-2606-1103)
- Cüneyt Bilginer
- Faruk Kılınç (ORCID: https://orcid.org/0000-0002-0198-2558)
- Ayten Oğuz (ORCID: https://orcid.org/0000-0002-9518-8610)
- Sema Taban (ORCID: https://orcid.org/0000-0001-6311-1232)
- Ramazan Sarı (ORCID: https://orcid.org/0000-0002-6989-1492)
- Süleyman Baldane (ORCID: https://orcid.org/0000-0002-7001-4075)
- Evin Bozkur (ORCID: https://orcid.org/0000-0002-3799-2125)
- Özen Öz Gül (ORCID: https://orcid.org/0000-0002-1332-4165)
- Hüseyin Yağcı (ORCID: https://orcid.org/0000-0002-2108-6347)
- Elif Güneş (ORCID: https://orcid.org/0000-0002-5441-2604)
- Mehmet Güven (ORCID: https://orcid.org/0000-0002-0752-8815)
- Arzu Or Koca (ORCID: https://orcid.org/0000-0001-8433-4769)
- Cevdet Duran (ORCID: https://orcid.org/0000-0001-9560-180X)
- İsmail Engin (ORCID: https://orcid.org/0000-0002-6493-9194)
- Eren Gürkan (ORCID: https://orcid.org/0000-0002-3118-4549)
- Sayid Shafi Zuhur (ORCID: https://orcid.org/0000-0001-8084-848X)
- Nergis Basmacı
- Mustafa Şahin
- Bekir Çakır (ORCID: https://orcid.org/0000-0001-7526-8827)
Institutions
- Çanakkale Onsekiz Mart Üniversitesi (TR)
- Tekirdağ Namık Kemal University (TR)
- Ministry of Health (TR)
- Bursa Uludağ Üni̇versi̇tesi̇ (TR)
- Selçuk University (TR)
- Fırat University (TR)
- Ankara University (TR)
- Karadeniz Technical University (TR)
- University of Health Science (KH)
- Bursa Technical University (TR)
- Akdeniz University (TR)
- Usak University (TR)
- Kütahya Dumlupınar Üniversitesi (TR)
- Iğdır Üniversitesi (TR)
- Memorial Ankara Hospital (TR)
- Ankara Onkoloji Eğitim ve Araştırma Hastanesi (TR)
- Ümraniye Eğitim ve Araştırma Hastanesi (TR)
- Istinye University (TR)
- Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi (TR)
- Education Training And Research (US)
- Sağlık Bilimleri Üniversitesi (TR)
- Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR)
- Kutahya Saglik Bilimleri Universitesi
- Mustafa Kemal University (TR)
- Kahramanmaraş Sütçü İmam University (TR)
- Pamukkale University (TR)
- Hacettepe University (TR)
- Istanbul University (TR)
- Muğla University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1111/cen.70024
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00