TFE3 immunohistochemistry in renal cell carcinomas: does the clone really matter?
The TFE3-MRQ37 clone is easier to interpret because of the absence of background staining and is more reliable in identifying TFE3 rearranged renal cell carcinomas. However, because of various sensitivity and specificity rates, and immunoreactivity in many subtypes of renal cell carcinomas, there is a need for a standardised approach for TFE3 immunohistochemistry for diagnostic use in TFE3-tRCCs.
Authors
- Tuba Ünal (ORCID: https://orcid.org/0000-0003-3981-6026)
Institutions
- Bilkent University (TR)
- Memorial Ankara Hospital (TR)
- Başkent University Hospital (TR)
- Ankara Yıldırım Beyazıt University (TR)
Publication Details
- Journal
- Northern Clinics of Istanbul
- Published
- 2025-01-01
- DOI
- https://doi.org/10.14744/nci.2024.19794
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00