Prenatal exposure to a mixture of per- and polyfluoroalkyl substances (PFAS) and lung function and immune-related outcomes among males in childhood and young adulthood
Prenatal PFAS exposure was associated with lower FEV<sub>1</sub> and FVC in a cohort of young adult males, suggesting an impact on lung development. Associations with reduced hay fever in childhood may suggest influences on immune maturation. Potential sex-specific effects should be addressed in future studies.
Authors
- Kajsa Ugelvig Petersen (ORCID: https://orcid.org/0000-0002-7370-6800)
- Sandra Søgaard Tøttenborg (ORCID: https://orcid.org/0000-0001-7742-4360)
- Cecilia Høst Ramlau‐Hansen (ORCID: https://orcid.org/0000-0003-3296-0121)
- Zeyan Liew (ORCID: https://orcid.org/0000-0002-9424-7869)
- Esben Meulengracht Flachs (ORCID: https://orcid.org/0000-0002-2252-8426)
- Gunnar Toft (ORCID: https://orcid.org/0000-0002-7542-6853)
- Kelly K. Ferguson (ORCID: https://orcid.org/0000-0001-8467-3250)
- Stephanie J. London (ORCID: https://orcid.org/0000-0003-4911-5290)
- Jens Peter Bonde (ORCID: https://orcid.org/0000-0002-8181-3673)
- Sidsel Dan Hull (ORCID: https://orcid.org/0000-0001-6198-3256)
- Karin Sørig Hougaard (ORCID: https://orcid.org/0000-0002-3386-0512)
- Christian H. Lindh (ORCID: https://orcid.org/0000-0001-7435-9890)
- Lauren Anne Wise (ORCID: https://orcid.org/0000-0003-2138-3752)
- Allen J. Wilcox (ORCID: https://orcid.org/0000-0002-3376-1311)
Institutions
- Boston University (US)
- National Institutes of Health (US)
- Steno Diabetes Centers (DK)
- Lund University (SE)
- Aarhus University (DK)
- Frederiksberg Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Yale University (US)
- National Institute of Environmental Health Sciences (US)
- National Research Centre for the Working Environment (DK)
Publication Details
- Journal
- Environmental Research
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1016/j.envres.2025.122746
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dagmar Marshalls Fond
- Aarhus Universitet
- Aarhus Universitetshospital
- Sundhed og Sygdom, Det Frie Forskningsråd
- Innovationsfonden
- European Commission
- National Research Foundation
- Danmarks Grundforskningsfond
- Lunds Universitet
- Lundbeckfonden
- Novo Nordisk
- Nordea-fonden
- Danmarks Frie Forskningsfond
- Region Hovedstaden
- A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal
- Helsefonden
- Egmont Fonden
- H. Lundbeck A/S
- National Institutes of Health
- Medical Research Council
- National Institute of Environmental Health Sciences