Herpes simplex virus disease in infants younger than 90 days: a British Paediatric Surveillance Unit study
Infants with neonatal HSV can present without fever, SEM lesions or elevated infection markers; treatment delay is subsequently common. Outcomes remain poor with high case-fatality rates and long-term morbidity. Clinicians should have a low threshold for empirically testing for and treating herpes in unwell neonates.
Authors
- Sonia Ribeiro (ORCID: https://orcid.org/0000-0002-9641-4392)
- Paul Trafford Heath (ORCID: https://orcid.org/0000-0002-7540-7433)
- Shamez Ladhani (ORCID: https://orcid.org/0000-0002-0856-2476)
- Katy Fidler (ORCID: https://orcid.org/0000-0001-6947-5205)
- Annalie Shears (ORCID: https://orcid.org/0000-0002-8558-2999)
- Georgina Yan (ORCID: https://orcid.org/0000-0001-5129-5214)
- Julia Dudley (ORCID: https://orcid.org/0000-0002-3746-7726)
Institutions
- Brighton and Sussex Medical School (GB)
- St George's, University of London (GB)
- Royal Alexandra Children's Hospital (GB)
- Homerton University Hospital (GB)
- UK Health Security Agency (GB)
- University of Brighton (GB)
Publication Details
- Journal
- Archives of Disease in Childhood
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/archdischild-2025-329176
- Citations
- 2
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.71