A Case Study on Wolfram Syndrome: Medical and Nursing Management

Abstract The uncommon genetic ailment known as Wolfram syndrome (WS) is regarded as the most representative example of endoplasmic reticulum disorders. Childhood-onset diabetes mellitus, ocular atrophy, deafness, diabetes insipidus, neurological symptoms and other anomalies are considered classic hallmarks of WS, which is rare. It has been determined that WFS1 and WFS2 are the two causal genes. While there are yet no effective therapies to stop or reverse the course of WS, patients can experience less suffering and a higher quality of life with the use of supportive care and close clinical monitoring. In this article, we discuss about nursing care of an adolescent with WS.