Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness
This study clarified platelet antibody distribution in Chinese iPTR patients. Besides HLA Class I antibodies, autoantibodies against platelet glycoproteins play a key role. Among HPA antibodies, HPA-5b may predominate in the Chinese population instead of HPA-1a.
Authors
- Xiaozhen Hong (ORCID: https://orcid.org/0000-0002-6440-0412)
- Xianguo Xu (ORCID: https://orcid.org/0000-0002-1630-8144)
- Kairong Ma (ORCID: https://orcid.org/0000-0001-9281-1086)
- Bing Zhang (ORCID: https://orcid.org/0000-0002-1750-1659)
- Ying Liu (ORCID: https://orcid.org/0000-0002-6540-0473)
- Xinyu Huang (ORCID: https://orcid.org/0000-0001-5976-1988)
- Faming Zhu (ORCID: https://orcid.org/0000-0002-1963-9176)
- Zhipan Wu (ORCID: https://orcid.org/0000-0002-8677-5928)
Institutions
- Blood Center of Zhejiang Province (CN)
Publication Details
- Journal
- Hematology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1080/16078454.2025.2549969
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Scientific Education and Research Foundation
- Health and Medical Research Fund
- Natural Science Foundation of Zhejiang Province