Microbiota composition and intestinal barrier function modulated by tamsulosin and Lactococcus lactis in a cirrhosis rat model
Findings such as reduced bacterial translocation, lower systemic endotoxin levels, improved intestinal morphology, and modulation of gut microbiota composition suggest that both agents (<i>L. lactis</i> and tamsulosin), particularly in combination, exert positive effects on the intestinal barrier in cirrhosis.
Authors
- Javier Ventura‐Juárez (ORCID: https://orcid.org/0000-0002-3083-0131)
- David Alejandro Hernández-Marín (ORCID: https://orcid.org/0000-0003-4978-294X)
- Abraham Loera‐Muro (ORCID: https://orcid.org/0000-0002-3163-1847)
- Martín Humberto Muñoz‐Ortega (ORCID: https://orcid.org/0000-0002-1961-6919)
- Sandra Luz Martínez-Hernández (ORCID: https://orcid.org/0000-0001-9714-1974)
- Silvia Valeria Padilla-García
Institutions
- Autonomous University of Aguascalientes (MX)
- Northwest Hospital (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fcimb.2025.1624065
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81