Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed
Cutaneous cryptococcosis is rarely caused by <i>Naganishia albidus</i>, especially in immunocompetent individuals. We report a unique case of perioral cutaneous infection in a 37-year-old male with scattered erythematous, pruritic, and scaly lesions lasting over a month. Initial clinical presentation mimicked common dermatological conditions, leading to potential misdiagnosis. Diagnosis was confirmed through fungal culture, fluorescence microscopy, MALDI-TOF mass spectrometry and molecular identification. The patient was successfully treated with oral itraconazole and topical fluconazole cream for six weeks. This case underscores the importance of considering rare fungal infections in atypical presentations to prevent misdiagnosis and delays in treatment.
Authors
- Dong-Hui Lu
- Wanqing Liao (ORCID: https://orcid.org/0000-0003-4454-5988)
- Dongyan Zheng
- Liuwei Liao
- Kaisu Pan
- Cunwei Cao (ORCID: https://orcid.org/0000-0002-6279-0322)
- Weixuan Wu
- Ping Luo (ORCID: https://orcid.org/0009-0006-9471-3264)
- Liang Dong (ORCID: https://orcid.org/0000-0003-0286-9001)
Institutions
- Guangxi Medical University (CN)
- People’s Hospital of Wenshan Prefecture (CN)
- Shanghai Changzheng Hospital (CN)
- Hegang People's Hospital (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Guangxi Center for Disease Prevention and Control (CN)
- Jingning County People's Hospital (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/idr.s514483
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Guangxi Province
- National Key Research and Development Program of China