Correlation between MGMT methylation and the efficacy of bevacizumab in high-grade glioma
Based on the exclusion of the interference from chemotherapy drugs, our study is the first to confirm the correlation between the methylation status of MGMT and the therapeutic effect of BEV on HGG.
Authors
- Wenbin Ma (ORCID: https://orcid.org/0000-0003-4800-7992)
- Xuexue Bai (ORCID: https://orcid.org/0000-0002-3841-6453)
- Chao Wu (ORCID: https://orcid.org/0000-0002-6193-4398)
- Chengrui Yan (ORCID: https://orcid.org/0000-0003-4533-8905)
- Ming Feng
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Tengzhou Central People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fonc.2025.1644934
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Science and Technology Major Project