Cerebellar-limbic dysregulation and sensorimotor network alterations in male primary insomnia: a resting-state functional magnetic resonance imaging study
Male patients with ID exhibit functional abnormalities in the cerebellum-limbic system circuit and the sensorimotor network. These alterations are accompanied by impaired motor coordination, dysregulated emotional processing, and deficits in sensory integration. Although ALFF and ReHo metrics show no significant correlation with the severity of clinical symptoms, the regional distribution patterns of these indicators across different brain areas suggest that they may serve as an index for ID, rather than a direct reflection of symptomatic manifestations.
Authors
- Zhenxiang Yuan
- Jie Zhao (ORCID: https://orcid.org/0000-0002-9226-0250)
- Jianda Hu (ORCID: https://orcid.org/0000-0002-4438-2544)
- Yong Liu (ORCID: https://orcid.org/0000-0002-1862-3121)
- Jinjin Yue
- Juan Lü (ORCID: https://orcid.org/0000-0002-9139-0678)
- Pingping Jie
- Haiyi Zhang
Institutions
- Southwest Medical University (CN)
- Neijiang Normal University (CN)
- Xian Yang Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fnhum.2025.1633506
- Citations
- 1
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Southwest Medical University
- Health Commission of Sichuan Province