Cerebellar-limbic dysregulation and sensorimotor network alterations in male primary insomnia: a resting-state functional magnetic resonance imaging study

Male patients with ID exhibit functional abnormalities in the cerebellum-limbic system circuit and the sensorimotor network. These alterations are accompanied by impaired motor coordination, dysregulated emotional processing, and deficits in sensory integration. Although ALFF and ReHo metrics show no significant correlation with the severity of clinical symptoms, the regional distribution patterns of these indicators across different brain areas suggest that they may serve as an index for ID, rather than a direct reflection of symptomatic manifestations.

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Publication Details

Journal
Frontiers in Human Neuroscience
Published
2025-09-02
DOI
https://doi.org/10.3389/fnhum.2025.1633506
Citations
1
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
1.43

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article

Cerebellar-limbic dysregulation and sensorimotor network alterations in male primary insomnia: a resting-state functional magnetic resonance imaging study

Zhenxiang Yuan, Jie Zhao, Jianda Hu, Yong Liu et al.
1 citations
Frontiers in Human Neuroscience
Sleep and Wakefulness Research
1.43
article

Cerebellar-limbic dysregulation and sensorimotor network alterations in male primary insomnia: a resting-state functional magnetic resonance imaging study

Zhenxiang Yuan, Jie Zhao, Jianda Hu, Yong Liu, Jinjin Yue, Juan Lü, Pingping Jie, Haiyi Zhang
article en
1 citations

Abstract

Male patients with ID exhibit functional abnormalities in the cerebellum-limbic system circuit and the sensorimotor network. These alterations are accompanied by impaired motor coordination, dysregulated emotional processing, and deficits in sensory integration. Although ALFF and ReHo metrics show no significant correlation with the severity of clinical symptoms, the regional distribution patterns of these indicators across different brain areas suggest that they may serve as an index for ID, rather than a direct reflection of symptomatic manifestations.

Frontiers in Human NeuroscienceVol. 19
Southwest Medical University (CN), Neijiang Normal University (CN), Xian Yang Central Hospital (CN)
Southwest Medical University, Health Commission of Sichuan Province
Openalex Percentile: Top 16%
Sleep and Wakefulness Research
1.43
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