Successful rescue of a rare case of refractory shock due to multidrug toxicity: a case report
The treatment of mixed drug poisoning involving reserpine, metformin, and enalapril is very challenging. When resuscitating patients with refractory shock caused by such poisoning, early supportive therapies should be started, including gastric lavage, cathartic use, acid correction, improved ventilation, blood purification, and hemodialysis when needed. Additionally, vasoactive drugs may be given without an upper dose limit, as long as side effects are carefully monitored.
Authors
- Yunxing Cao
- Yujie Zhou (ORCID: https://orcid.org/0000-0002-2968-2952)
- Yuanyang Xie (ORCID: https://orcid.org/0000-0001-9655-0805)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fphar.2025.1669831
- Primary Topic
- Poisoning and overdose treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00