Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma

The proposed glycosylation-related gene signature accurately distinguishes between high- and low-risk STS patients and may serve as a reliable prognostic tool. It also provides novel insights into tumor immune microenvironment and potential therapeutic targets for STS.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-09-02
DOI
https://doi.org/10.3389/fonc.2025.1636830
Primary Topic
Glycosylation and Glycoproteins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma

Ningning Yuan, Junhui Yuan, Yutong Gao, Jinfeng Zhang et al.
Frontiers in Oncology
Glycosylation and Glycoproteins Research
article

Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma

Ningning Yuan, Junhui Yuan, Yutong Gao, Jinfeng Zhang, Xie Zhou, Guowei Zuo, Y. Gao, M. Zawwad Raza
article en

Abstract

The proposed glycosylation-related gene signature accurately distinguishes between high- and low-risk STS patients and may serve as a reliable prognostic tool. It also provides novel insights into tumor immune microenvironment and potential therapeutic targets for STS.

Frontiers in OncologyVol. 15
Qingdao University (CN), Ministry of Education (SA), Ministry of Education (TH), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Qingdao Women and Children's Hospital (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 80%
Glycosylation and Glycoproteins Research
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Construction of a glycosylation-related prognostic signature for predicting prognosis, tumor microenvironment, and immune response in soft tissue sarcoma — Ningning Yuan, Junhui Yuan, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS