The Role of the Complement <scp>C3</scp> ‐Hippocampus Pathway in Relation With Mood Symptoms in Offspring of Parents With Bipolar Disorder
Our findings indicate a C3-hippocampus-depressive symptom pathway might underpin the particular high vulnerability of individuals with both familial and symptomatic risks of mood disorders. This evidence provides new neuroinflammatory markers and targets for early identification and intervention of these individuals.
Authors
- Robin Shao (ORCID: https://orcid.org/0009-0003-5370-1599)
- Kangguang Lin (ORCID: https://orcid.org/0000-0003-4027-5554)
- Jingui Chen (ORCID: https://orcid.org/0000-0002-4752-1204)
- Suk‐Yu Yau (ORCID: https://orcid.org/0000-0002-7425-6741)
- Zhongwan Liu
- Xiaoyue Li (ORCID: https://orcid.org/0000-0001-9149-7152)
- Wenjin Zou (ORCID: https://orcid.org/0000-0002-1768-5793)
- Weicong Lu
- Shiyun Wu (ORCID: https://orcid.org/0009-0004-2952-4606)
Institutions
- Hong Kong Polytechnic University (HK)
- Chinese University of Hong Kong (HK)
- The First People's Hospital of Shunde (CN)
- Qingdao Eighth People's Hospital (CN)
- Guangdong 999 Brain Hospital (CN)
- University of Hong Kong (HK)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Bipolar Disorders
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1111/bdi.70056
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China