Pharmacovigilance-based 12-year post-marketing safety analysis of quadrivalent influenza vaccines in children: a VAERS surveillance study
This pharmacovigilance analysis demonstrates generally favorable safety profiles for pediatric QIVs, with cell culture formulations showing superior safety characteristics. The extremely low absolute risk of Guillain-Barré syndrome supports continued routine pediatric influenza vaccination while highlighting the importance of platform-specific safety monitoring.
Authors
- Yubei Huang (ORCID: https://orcid.org/0000-0002-6299-7112)
- Hong-Min Fu
- Yiji Su (ORCID: https://orcid.org/0000-0002-9902-0145)
- Yijie Liu (ORCID: https://orcid.org/0000-0002-2797-8776)
- Lili Pan (ORCID: https://orcid.org/0000-0003-0258-5367)
- Ying Zhang (ORCID: https://orcid.org/0009-0003-5645-8299)
- Xiaolu Wang
Institutions
- Fujian Medical University (CN)
- Fujian Institute of Microbiology (CN)
- Fujian Special Equipment Inspection Institute (CN)
- Xiamen Chang Gung Hospital (CN)
- Union Hospital (CN)
- Fujian Inspection and Research Institute for Product Quality (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fped.2025.1640498
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00