Fractional Amplitude of Low-Frequency Fluctuations and Regional Homogeneity Analyses Revealed Altered Local Spontaneous Neural Activities in Ankylosing Spondylitis
The fALFF and ReHo analyses consistently revealed significantly altered local spontaneous neural activities in AS patients, especially in the DMN, SN and FPN, comprising the triple network model. The slow-4 band might be more sensitive to the elevated fALFF values in AS patients than the slow-5 band. Our findings provide further evidence that the aberrations of the triple network model serve as an important feature of AS from the perspective of local neural activities.
Authors
- Budian Liu (ORCID: https://orcid.org/0000-0002-0800-8619)
- Ya Xie (ORCID: https://orcid.org/0000-0002-1840-3890)
- Jie Qin (ORCID: https://orcid.org/0000-0002-5000-5817)
- Churong Lin
- Xiaohong Wang (ORCID: https://orcid.org/0000-0001-8557-0405)
- Dong Liu (ORCID: https://orcid.org/0000-0001-7562-2945)
- Jieruo Gu (ORCID: https://orcid.org/0000-0002-8785-0600)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/jpr.s515977
- Primary Topic
- Infrared Thermography in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sun Yat-sen University