Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis
Our findings may give further insights into manipulated mechanistic pathways by IL-23 inhibition in patients with PSO and PSA.
Authors
- Maria Esposito (ORCID: https://orcid.org/0000-0002-4773-6993)
- Cristina Pellegrini (ORCID: https://orcid.org/0000-0003-2168-8097)
- Paola Cipriani (ORCID: https://orcid.org/0000-0002-2000-4661)
- Piero Ruscitti (ORCID: https://orcid.org/0000-0003-3487-8551)
- Maria Concetta Fargnoli (ORCID: https://orcid.org/0000-0002-7249-2556)
- Mirco Mastrangelo (ORCID: https://orcid.org/0000-0003-2232-7090)
- Manfredo Bruni (ORCID: https://orcid.org/0000-0001-9357-9653)
- Andrea De Berardinis (ORCID: https://orcid.org/0009-0008-6388-1438)
- Antonio Barile (ORCID: https://orcid.org/0000-0003-0253-3583)
- Eleonora Lucantonio
Institutions
- University of L'Aquila (IT)
- San Gallicano Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1672667
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi dell'Aquila