Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis

Our findings may give further insights into manipulated mechanistic pathways by IL-23 inhibition in patients with PSO and PSA.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-09-02
DOI
https://doi.org/10.3389/fimmu.2025.1672667
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00

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article

Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis

Maria Esposito, Cristina Pellegrini, Paola Cipriani, Piero Ruscitti et al.
Frontiers in Immunology
Psoriasis: Treatment and Pathogenesis
article

Assessment of gene signatures following the inhibition of IL-23: a study to evaluate the mechanistic effects behind the clinical efficacy of guselkumab in patients with psoriatic arthritis

Maria Esposito, Cristina Pellegrini, Paola Cipriani, Piero Ruscitti, Maria Concetta Fargnoli, Mirco Mastrangelo, Manfredo Bruni, Andrea De Berardinis, Antonio Barile, Eleonora Lucantonio
article en

Abstract

Our findings may give further insights into manipulated mechanistic pathways by IL-23 inhibition in patients with PSO and PSA.

Frontiers in ImmunologyVol. 16
University of L'Aquila (IT), San Gallicano Hospital (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Università degli Studi dell'Aquila
Openalex Percentile: Top 75%
Psoriasis: Treatment and Pathogenesis
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