An injectable curcumin-loaded hydrogel for neuroprotective treatment promote nerve tissue repair in rat severe spinal cord injury
These findings support the potential of CBT-gel to improve the microenvironment for spinal cord repair by leveraging their antioxidant and neuroprotective properties. The results in this study aligns with the documented bioactivity of curcumin, though molecular targets in the CBT-gel treatment require further profiling.
Authors
- Ruirui Tian
- Fanghui Zhao (ORCID: https://orcid.org/0000-0001-9294-0005)
- Hao Chen (ORCID: https://orcid.org/0000-0001-7654-5910)
- Guangwei Li (ORCID: https://orcid.org/0000-0003-1061-7293)
- Lifeng Xie (ORCID: https://orcid.org/0000-0001-6436-9008)
- Zhaoqing Zhang (ORCID: https://orcid.org/0000-0002-5670-618X)
- Haiyan Ma (ORCID: https://orcid.org/0000-0002-5106-7323)
Institutions
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fbioe.2025.1655686
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- State Administration of Traditional Chinese Medicine of the People's Republic of China
- Shandong First Medical University