Evaluating single nucleotide polymorphisms in beta - 2 - microglobulin – a theoretical study
The occurrence of SNP's in B2M is an important "random" event that can affect the structure of the protein. We attempted to evaluate the effect of SNP's on the primary structure of B2M and concluded that there is need to improve the computer software programs evaluating the effect of SNP's and other genetic modifications on the proteins as well as improving the scoring systems evaluating the AA substitutions.
Authors
- Ammar K. Daoud (ORCID: https://orcid.org/0000-0001-9579-471X)
- Wafa’ A. Alqarqaz
- Majduleen M. Al Okor
Institutions
- Jordan University of Science and Technology (JO)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-02
- DOI
- https://doi.org/10.3389/fimmu.2025.1622416
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00