The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

Patients with DTC presenting elevated preoperative levels of MLR, SIRI, and SII demonstrated a significantly higher incidence of multiple adverse clinicopathological features postoperatively compared to those with lower baseline inflammatory indicators levels. These findings suggest that MLR, SIRI, and SII may serve as predictive biomarkers for adverse tumor clinicopathological characteristics in DTC.

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Publication Details

Journal
Frontiers in Molecular Biosciences
Published
2025-09-02
DOI
https://doi.org/10.3389/fmolb.2025.1660379
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

Liyuan Yang, Ludi Yang
Frontiers in Molecular Biosciences
Inflammatory Biomarkers in Disease Prognosis
article

The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

Liyuan Yang, Ludi Yang
article en

Abstract

Patients with DTC presenting elevated preoperative levels of MLR, SIRI, and SII demonstrated a significantly higher incidence of multiple adverse clinicopathological features postoperatively compared to those with lower baseline inflammatory indicators levels. These findings suggest that MLR, SIRI, and SII may serve as predictive biomarkers for adverse tumor clinicopathological characteristics in DTC.

Frontiers in Molecular BiosciencesVol. 12
Shanghai Jiao Tong University (CN), Fudan University Shanghai Cancer Center (CN), Shanghai Sixth People's Hospital (CN)
Openalex Percentile: Top 68%
Inflammatory Biomarkers in Disease Prognosis
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The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma — Liyuan Yang, Ludi Yang · Frontiers in Molecular Biosciences (2025) | TGRS Research Map | TGRS