MALDI-TOF MS for identification of Afro-tropical secondary malaria vectors
The results provide evidence that MALDI-TOF can identify secondary malaria vectors from Eastern and Southeastern African regions. This technique was as efficient as DNA sequencing in identifying mosquito species. Indeed, except for An. cf coustani 2NFL-2015 and An. ziemanni, an exact species identification was obtained for all individual mosquitoes. These findings highlight the potential of MALDI-TOF MS for monitoring malaria vectors.
Authors
- Festus Mure
- Luis Miguel Constantino (ORCID: https://orcid.org/0000-0001-8117-5803)
- Derek Charlwood
- Brian Bartilol (ORCID: https://orcid.org/0000-0002-8945-0002)
- Rui Pei (ORCID: https://orcid.org/0000-0002-7742-5627)
- Carlos Chaccour (ORCID: https://orcid.org/0000-0001-9812-050X)
- Francisco Saúte (ORCID: https://orcid.org/0000-0002-9107-8094)
- Martin Kibet Rono (ORCID: https://orcid.org/0000-0002-7255-821X)
- Zedekiah Ondieki
- Peter Meli
- Jonathan Karisa (ORCID: https://orcid.org/0000-0002-3383-6782)
- Caroline Wanjiku (ORCID: https://orcid.org/0000-0003-3861-4190)
- Bruno Otieno
- Caroline Kiuru (ORCID: https://orcid.org/0000-0002-0179-5322)
- Baltazar Candrinho (ORCID: https://orcid.org/0000-0001-7373-6631)
- Tobias Odongo
- Marta F. Maia (ORCID: https://orcid.org/0000-0003-3302-5610)
- Regina Rabinovich (ORCID: https://orcid.org/0000-0003-1065-0173)
- Mercy Tuwei
- Edith Ramaita
- Charles Mbogo
- Joseph Mwangangi
- Gildo Cole
- Claudia Alves
- Miguel Okoko
- Rehema Gona
- Trisa Anastácio
- Romário Armazia
Institutions
- Angkor Hospital for Children (KH)
- Kenya Medical Research Institute (KE)
- Instituto Oncológico Dr. Rosell (ES)
- Instituto de Medicina Tropical (PY)
- Centro de Investigación Biomédica en Red (ES)
- Ministry of Health (KE)
- Manhiça Health Research Centre (MZ)
- National Directorate of Geology (MZ)
- Barcelona Institute for Global Health (ES)
- Universidad de Navarra (ES)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-09-02
- DOI
- https://doi.org/10.1186/s12936-025-05549-6
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- Helsingin Yliopisto
- Helsingin ja Uudenmaan Sairaanhoitopiiri