A Stability-Aware Dual-Head Network with Prototype-Based Consistency for Semi-Supervised Medical Image Segmentation

Semi-supervised semantic segmentation for medical images has evolved through time. While it can leverage the unlabeled data to significantly improve the segmentation performance, it still suffers the problems of intra-class variance and the consequent class-domain distribution misalignment along with costly training. In this paper, a stability-aware dual-head architecture is proposed to synergize prototype-based and Fully Convolutional Network (FCN) methodologies. By integrating prototype-based method for feature consistency and FCN method for spatial detail preservation, our method enforces consistency between different feature representations. It combines the semantic consistency of prototype learning with the precision of dense prediction. A sample-level stability-aware adaptive augmentation strategy is introduced to further mitigate intra-class variance and distribution shifts. The following certainty guided fusion process dynamically refines the pseudo-labels, better utilizing the advantages in different methods. Experiments on BraTS2019 and LA Heart demonstrate State-Of-The-Art (SOTA) performance, achieving significant improvements over the previous SOTA methods on multiple metrics. The framework effectively bridges domain gaps and enhances pseudo-label reliability for medical image analysis. (Code is available at https://github.com/Alfredzly/SDNP).

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Publication Details

Journal
International Journal of Neural Systems
Published
2025-08-29
DOI
https://doi.org/10.1142/s0129065725500546
Primary Topic
Advanced Neural Network Applications
Type
article
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article

A Stability-Aware Dual-Head Network with Prototype-Based Consistency for Semi-Supervised Medical Image Segmentation

Lei Zhang, Jiayi Li, Xiaolong Xu, Yan Yu et al.
International Journal of Neural Systems
Advanced Neural Network Applications
article

A Stability-Aware Dual-Head Network with Prototype-Based Consistency for Semi-Supervised Medical Image Segmentation

Lei Zhang, Jiayi Li, Xiaolong Xu, Yan Yu, Leyi Zhang
article en

Abstract

Semi-supervised semantic segmentation for medical images has evolved through time. While it can leverage the unlabeled data to significantly improve the segmentation performance, it still suffers the problems of intra-class variance and the consequent class-domain distribution misalignment along with costly training. In this paper, a stability-aware dual-head architecture is proposed to synergize prototype-based and Fully Convolutional Network (FCN) methodologies. By integrating prototype-based method for feature consistency and FCN method for spatial detail preservation, our method enforces consistency between different feature representations. It combines the semantic consistency of prototype learning with the precision of dense prediction. A sample-level stability-aware adaptive augmentation strategy is introduced to further mitigate intra-class variance and distribution shifts. The following certainty guided fusion process dynamically refines the pseudo-labels, better utilizing the advantages in different methods. Experiments on BraTS2019 and LA Heart demonstrate State-Of-The-Art (SOTA) performance, achieving significant improvements over the previous SOTA methods on multiple metrics. The framework effectively bridges domain gaps and enhances pseudo-label reliability for medical image analysis. (Code is available at https://github.com/Alfredzly/SDNP).

International Journal of Neural SystemsVol. 35(10)
Sichuan University (CN), Tianma Microelectronics (China) (CN)
Openalex Percentile: Top 78%
Advanced Neural Network Applications
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A Stability-Aware Dual-Head Network with Prototype-Based Consistency for Semi-Supervised Medical Image Segmentation — Lei Zhang, Jiayi Li, et al. · International Journal of Neural Systems (2025) | TGRS Research Map | TGRS