Changes in Pre- and Post-Treatment Gut Microbiota and Metabolites in Neonates With Hyperbilirubinemia
This study demonstrates significant treatment-associated shifts in gut microbiota and metabolites in hyperbilirubinemic neonates, suggesting microbial dysbiosis may contribute to altered bilirubin metabolism. These findings highlight the potential of early microbiome-targeted interventions for managing neonatal jaundice and identify candidate therapeutic targets and biomarkers.
Authors
- Yueyun Luo
- Yan Liu (ORCID: https://orcid.org/0000-0003-2649-2552)
- Longyi Mo
- Dongzi Lin
- Cheng Xu (ORCID: https://orcid.org/0009-0005-5551-2577)
- Qian-Qi Chen
- Minxiu Ye
Institutions
- Guangdong Medical College (CN)
- The Fourth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-08-30
- DOI
- https://doi.org/10.31083/fbl42716
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Leicester