The role of surgery in gastric cancer with liver metastases: A narrative review

Gastric cancer with liver metastases is one of the most fatal diseases with a dismal prognosis.At diagnosis, 14% of patients with gastric cancer have liver metastases.The gold standard in this setting of disease is chemotherapy; surgery just serves to reduce symptoms or halt gastrointestinal bleeding.However, ongoing retrospective investigations have demonstrated the value of surgery in cases of gastric cancer with liver metastases and the significantly higher survival rate of patients randomly assigned to receive surgery with or without chemotherapy.Therefore, more and stronger evidence from prospective randomized clinical trials is required to explain surgical methods for patients with gastric cancer who have limited liver metastases.

Authors

Publication Details

Journal
International Journal of Gastrointestinal Intervention
Published
2025-09-01
DOI
https://doi.org/10.18528/ijgii250051
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

The role of surgery in gastric cancer with liver metastases: A narrative review

Alfredo Colombo, Concetta Maria Porretto
1 links
International Journal of Gastrointestinal Intervention
Gastric Cancer Management and Outcomes
article

The role of surgery in gastric cancer with liver metastases: A narrative review

Alfredo Colombo, Concetta Maria Porretto
article en

Abstract

Gastric cancer with liver metastases is one of the most fatal diseases with a dismal prognosis.At diagnosis, 14% of patients with gastric cancer have liver metastases.The gold standard in this setting of disease is chemotherapy; surgery just serves to reduce symptoms or halt gastrointestinal bleeding.However, ongoing retrospective investigations have demonstrated the value of surgery in cases of gastric cancer with liver metastases and the significantly higher survival rate of patients randomly assigned to receive surgery with or without chemotherapy.Therefore, more and stronger evidence from prospective randomized clinical trials is required to explain surgical methods for patients with gastric cancer who have limited liver metastases.

International Journal of Gastrointestinal InterventionVol. 14(4)
Openalex Percentile: Top 66%
Gastric Cancer Management and Outcomes
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The role of surgery in gastric cancer with liver metastases: A narrative review — Alfredo Colombo, Concetta Maria Porretto · International Journal of Gastrointestinal Intervention (2025) | TGRS Research Map | TGRS