A Tale of Many Canadas: Associations of Ancestry With Juvenile Idiopathic Arthritis Categories and Disease Severity at Presentation to Care
British and French ancestries had distinct associations with JIA categories and cJADAS10 scores, and many children had multiple ancestries, questioning the use of a single "European" reference group. Higher cJADAS10 scores were largely explained by differences in JIA categories across ancestries.
Authors
- Kristin Houghton (ORCID: https://orcid.org/0000-0001-7174-1007)
- David A. Cabral (ORCID: https://orcid.org/0000-0003-1840-9210)
- Kiem Oen (ORCID: https://orcid.org/0000-0002-3331-9662)
- Lori B. Tucker (ORCID: https://orcid.org/0000-0002-4314-6750)
- Roberta Audrey Berard (ORCID: https://orcid.org/0000-0003-2780-0617)
- Gaëlle Chédeville (ORCID: https://orcid.org/0000-0001-9702-7776)
- Rae S. M. Yeung (ORCID: https://orcid.org/0000-0003-2361-725X)
- Ciarán M. Duffy (ORCID: https://orcid.org/0000-0003-2481-5450)
- Mercedes Chan (ORCID: https://orcid.org/0000-0002-8715-5931)
- Kimberly Morishita (ORCID: https://orcid.org/0000-0002-1389-4002)
- Stephanie Wong (ORCID: https://orcid.org/0000-0002-3237-1725)
- Jaime Guzmán (ORCID: https://orcid.org/0000-0001-8977-2581)
- Thomas M. Loughin
Institutions
- Western University (CA)
- University of British Columbia (CA)
- University of Ottawa (CA)
- Simon Fraser University (CA)
- University of Toronto (CA)
- Children's Hospital of Eastern Ontario (CA)
- London Health Sciences Centre (CA)
- Hospital for Sick Children (CA)
- McGill University Health Centre (CA)
- SickKids Foundation (CA)
- BC Children's Hospital (CA)
- University of Manitoba (CA)
- McGill University (CA)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-08-31
- DOI
- https://doi.org/10.1002/acr2.70092
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- BC Children's Hospital
- Canadian Institutes of Health Research