Physiology of the rat intestinal allograft: a dextran-based study of motility and permeability
Background: Intestinal transplantation (ITx) is a life-saving procedure for patients with complicated intestinal failure. In the acute phase, allograft permeability increases primarily due to ischemia-reperfusion injury. However, long-term allograft physiology after transplantation remains poorly understood, particularly the impact of lost autonomous graft innervation. This study aims to evaluate post-ITx allograft motility and absorption using orally administered fluorescein-labeled dextrans (TRITC70,FITC4).
Authors
- Alice Rustichelli (ORCID: https://orcid.org/0000-0002-1214-3979)
- Tine Wylin
- Veerle Heedfeld (ORCID: https://orcid.org/0009-0008-3741-8343)
- Caroline Boelhouwer (ORCID: https://orcid.org/0000-0002-7143-4864)
- Ricard Farré (ORCID: https://orcid.org/0000-0001-7158-171X)
- Jacques Pirenne (ORCID: https://orcid.org/0000-0002-8147-8801)
- Laurens J. Ceulemans (ORCID: https://orcid.org/0000-0002-4261-7100)
- Tim Vanuytsel (ORCID: https://orcid.org/0000-0001-8728-0903)
- Antoine Dubois (ORCID: https://orcid.org/0000-0002-2839-8896)
- Amelie Leenders
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- Intestinal failure.
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.intf.2025.100281
- Primary Topic
- Clinical Nutrition and Gastroenterology
- Type
- article
- Field-Weighted Citation Impact
- 0.00