Trending Microbiome Dysbiosis Over Time as an Early Assessment of Intestinal Transplant Rejection Risk

Background: Young adulthood (18-25 years) is a critical period of transition toward independence.For transplant recipients, these challenges are compounded by the need for regular healthcare visits, responsibility for life-long medication, adherence to self-care routines and healthy lifestyle habits along with the psychological burden of rejection or other complications.As survival rates improve, an increasing number of paediatric transplant recipients transition to adult care.While many patients and relatives report satisfaction with the transfer, studies also describe dissatisfaction, highlighting the need for improvement.Young adulthood has also proven to be a critical period when it comes to organ rejection and graft loss.Methods: Dedicated reception days are organized exclusively for patients 18 to 25 years of age.In addition to scheduled visits to physicians and nurses, patients can spontaneously book consultations with a dietitian, physiotherapist, social worker, or rehab coordinator.A key component of the clinic is a lunchtime lecture series, supported by the Jonte Foundation, with topics selected by the young patients themselves.The Jonte Foundation also organizes an evening social event.Results: The Young-Adult Clinic is now an established, wellattended and appreciated part of the Transplant Centre, both by patients, caregivers, and staff.Lectures delivered by fellow transplant recipients are particularly appreciated, underscoring the importance for peer support and shared experiences.Conclusions: The Young-Adult Clinic has become an integral part of the transition process.By focusing on the specific needs, challenges and risks faced by young adults, the clinic has the potential to improve self-care, independence, adherence to medication, and lifestyle recommendations.