Development of a Short Bowel Syndrome Model Using the smallest experimental pig

Background: This study reports the development of a long-term short bowel syndrome (SBS) model using the Microminipig (MMP), the smallest experimental pig in the world, with an adult weight of ≤30 kg. Unlike previous porcine SBS models, which required intensive nutritional support and had limited survival periods, this model demonstrated extended survival without the need for postoperative parenteral nutrition (PN).