Intestinal preservation using luminal perfusion preservation and aeration: a small animal study

Background: Solid organ preservation has recently witnessed the development of hypothermic and normothermic machine perfusion and oxygenation systems. These approaches have shown improved results in liver transplantation however few studies have been made on intestinal tissue. We have compared the standard practice of intestinal static cold storage (SCS) with the combined approach of IGL-1 and luminal PEG solution as well as luminal solution with the addition of air insufflation into a closed preservation solution system.

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Publication Details

Journal
Intestinal failure.
Published
2025-01-01
DOI
https://doi.org/10.1016/j.intf.2025.100218
Primary Topic
Hydrogen's biological and therapeutic effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Intestinal preservation using luminal perfusion preservation and aeration: a small animal study

Mats Hellström, Mihai Oltean, Anna Casselbrant, Arvind Manikantan Padma et al.
Intestinal failure.
Hydrogen's biological and therapeutic effects
article

Intestinal preservation using luminal perfusion preservation and aeration: a small animal study

Mats Hellström, Mihai Oltean, Anna Casselbrant, Arvind Manikantan Padma, Jasmine Bagge, Gustav Hagberg
article en

Abstract

Background: Solid organ preservation has recently witnessed the development of hypothermic and normothermic machine perfusion and oxygenation systems. These approaches have shown improved results in liver transplantation however few studies have been made on intestinal tissue. We have compared the standard practice of intestinal static cold storage (SCS) with the combined approach of IGL-1 and luminal PEG solution as well as luminal solution with the addition of air insufflation into a closed preservation solution system.

Intestinal failure.Vol. 6
Sahlgrenska University Hospital (SE), University of Gothenburg (SE)
Openalex Percentile: Top 63%
Hydrogen's biological and therapeutic effects
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