Bulk and Single-Cell Transcriptomes Reveal Exhausted Signature in Prognosis of Hepatocellular Carcinoma

This study provides a comprehensive characterization of the TEX landscape in HCC and identifies a robust gene signature associated with prognosis and immune infiltration. These findings highlight the potential of targeting TEX-related genes for personalized immunotherapeutic strategies in HCC.

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Publication Details

Journal
Genes
Published
2025-08-30
DOI
https://doi.org/10.3390/genes16091034
Citations
1
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
1.52

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article

Bulk and Single-Cell Transcriptomes Reveal Exhausted Signature in Prognosis of Hepatocellular Carcinoma

Ruthanne Chun, Ziyi Zhao, Chunlong Zhang, Haisen Ni
1 citations
Genes
Ferroptosis and cancer prognosis
1.52
article

Bulk and Single-Cell Transcriptomes Reveal Exhausted Signature in Prognosis of Hepatocellular Carcinoma

Ruthanne Chun, Ziyi Zhao, Chunlong Zhang, Haisen Ni
article en
1 citations

Abstract

This study provides a comprehensive characterization of the TEX landscape in HCC and identifies a robust gene signature associated with prognosis and immune infiltration. These findings highlight the potential of targeting TEX-related genes for personalized immunotherapeutic strategies in HCC.

GenesVol. 16(9)
Northeast Forestry University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Heilongjiang Province
Openalex Percentile: Top 15%
Ferroptosis and cancer prognosis
1.52
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