Development and Performance Validation of a Comprehensive Liquid Biopsy Genotyping Panel for Pan-cancer Analysis
The PAN100 panel is a robust tool for detecting clinically significant variants with high concordance with tissue NGS. Its sensitivity for low-frequency variants enables real-time treatment adaptation, supporting precision oncology. Its comprehensive design is particularly valuable for challenging diagnoses and clonal evolution monitoring.
Authors
- Kwang Seob Lee (ORCID: https://orcid.org/0000-0002-6286-108X)
- Jieun Seo (ORCID: https://orcid.org/0000-0002-0490-6059)
- Sung Hyun Seo (ORCID: https://orcid.org/0000-0001-7723-9317)
- Dongju Won (ORCID: https://orcid.org/0000-0002-0084-0216)
- Jong Rak Choi (ORCID: https://orcid.org/0000-0002-0608-2989)
- Seung‐Tae Lee (ORCID: https://orcid.org/0000-0003-1047-1415)
- Saeam Shin (ORCID: https://orcid.org/0000-0003-1501-3923)
- Seoyoung Lim (ORCID: https://orcid.org/0009-0004-7944-2756)
Institutions
- Yonsei University (KR)
- Washington University in St. Louis (US)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2025-09-01
- DOI
- https://doi.org/10.3343/alm.2025.0171
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation of Korea