Adverse events during pregnancy, circulating metabolites, and congenital malformations: a Mendelian randomization study
MR was employed to elucidate the mediating role of circulating metabolites in the impact of these adverse events on congenital malformations, providing new insights into their causal relationships. However, the underlying mechanisms remain unclear, necessitating further research and clinical trials to elucidate these relationships.
Authors
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0003-1420-0567)
- Xiaohan Qin (ORCID: https://orcid.org/0000-0001-6895-4191)
- Yang� Yang (ORCID: https://orcid.org/0000-0003-1222-1209)
- Jingyue Wang (ORCID: https://orcid.org/0000-0001-8796-9612)
- Yongcheng Fu
- Xing Zhou
- Da Zhang (ORCID: https://orcid.org/0000-0003-4914-3777)
- Xiao Song Dong
- Jian Cheng (ORCID: https://orcid.org/0000-0003-1289-2758)
Institutions
- Fujian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1186/s12884-025-07860-1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Key Scientific Research Project of Colleges and Universities in Henan Province