Potential and mechanism of celery as a supportive therapy for hypertension: A review

Background: Celery (Apium graveolens L.) shows promise as a medicinal plant with significant potential for supportive therapy in hypertension. Research indicates that the combination of celery with synthetic antihypertensive drugs lowers blood pressure more effectively than using either component alone. Objective: To highlight the potential and mechanisms of celery in managing hypertension and encourage further research on its application in various easy-to-consume dosage forms. Method: Both national and international journals were searched on search engines, including Google Scholar, NCBI, PubMed, and several others, using keywords such as celery, content, hypertension, medicinal plants, and Apium graveolens. The data analysis used for evaluation was conducted through descriptive analysis. Results: Celery contains bioactive compounds such as Luteolin, Linalool, D-limonene, Apigenin, 3-n-butylphthalide, Kalium, Asparagine, Phthalides, Magnesium and other related compounds. The compounds play vital roles in controlling hypertension through several mechanisms, including the vasodilation of blood vessels. Conclusion: Celery has great potential as a supportive therapy for hypertension through various mechanisms of active compounds found in celery. Furthermore, advancements in celery-based medical formulations can enhance the ease of utilising celery as an adjunct therapy.