Intradural extramedullary solitary plasmacytoma originating in the cervical spine in the setting of refractory multiple myeloma: illustrative case

SP should be included in the differential diagnosis for intradural extramedullary lesions found in the spine, particularly in patients with a history of MM and tumor resistance to radiotherapy. Despite plasmacytoma's classically radiosensitive nature, it is possible to have residual tumor after radiation therapy. In these cases, patients may benefit greatly from surgical biopsy and decompression followed by adjuvant radiotherapy. https://thejns.org/doi/10.3171/CASE24731.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-08-25
DOI
https://doi.org/10.3171/case24731
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
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article

Intradural extramedullary solitary plasmacytoma originating in the cervical spine in the setting of refractory multiple myeloma: illustrative case

Carlin Chuck, Patricia Zadnik Sullivan, Michael Punsoni, Elaina J. Wang et al.
Journal of Neurosurgery Case Lessons
Multiple Myeloma Research and Treatments
article

Intradural extramedullary solitary plasmacytoma originating in the cervical spine in the setting of refractory multiple myeloma: illustrative case

Carlin Chuck, Patricia Zadnik Sullivan, Michael Punsoni, Elaina J. Wang, Giovanni Kozel
article en

Abstract

SP should be included in the differential diagnosis for intradural extramedullary lesions found in the spine, particularly in patients with a history of MM and tumor resistance to radiotherapy. Despite plasmacytoma's classically radiosensitive nature, it is possible to have residual tumor after radiation therapy. In these cases, patients may benefit greatly from surgical biopsy and decompression followed by adjuvant radiotherapy. https://thejns.org/doi/10.3171/CASE24731.

Journal of Neurosurgery Case LessonsVol. 10(8)
Brown University (US)
Openalex Percentile: Top 70%
Multiple Myeloma Research and Treatments
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