Isotopic labelling analysis using single cell mass spectrometry

In this proof-of-concept work, we applied single-cell mass spectrometry to track the incorporation of an isotopically labelled precursor into plant specialized metabolites. The application of stable-isotope labelling to single cell systems could provide a unique window into the dynamics of synthesis and intercellular transport of structurally complex metabolites.

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Publication Details

Journal
The Analyst
Published
2025-01-01
DOI
https://doi.org/10.1039/d5an00657k
Primary Topic
Isotope Analysis in Ecology
Type
article
Field-Weighted Citation Impact
0.00

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article

Isotopic labelling analysis using single cell mass spectrometry

Sarah E. O’Connor, Anh Hai Vu, Lorenzo Caputi
The Analyst
Isotope Analysis in Ecology
article

Isotopic labelling analysis using single cell mass spectrometry

Sarah E. O’Connor, Anh Hai Vu, Lorenzo Caputi
article en

Abstract

In this proof-of-concept work, we applied single-cell mass spectrometry to track the incorporation of an isotopically labelled precursor into plant specialized metabolites. The application of stable-isotope labelling to single cell systems could provide a unique window into the dynamics of synthesis and intercellular transport of structurally complex metabolites.

The AnalystVol. 150(22)
Max Planck Institute for Chemical Ecology (DE)
Max-Planck-Gesellschaft
Openalex Percentile: Top 77%
Isotope Analysis in Ecology
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