Does Intercommissural Distance Shortening in Bicuspid Aortic Valve Repair Improve Valve Opening Area?

BACKGROUND Standardized bicuspid aortic valve (BAV) repair makes 2 symmetrical cusps by plicating the fused cusp, which is accompanied by risk of aortic stenosis.Here, the effect of improving cusp mobility by shortening the intercommissural distance (ICD) on increasing the aortic valve area was examined in a BAV model using a pulsatile flow simulator.METHODS Six pairs of symmetrical BAV were created in a neo-Valsalva graft with bovine pericardium (free margin length, 26 mm; geometric height, 20 mm), which were incorporated into a pulsation circuit simulator.The ICD was gradually shortened, and the forward flow, leakage flow, pressure gradient, and aortic valve area were measured.The average value of a total of 18 measurements (3 for each model) was examined. RESULTSForward flow remained constant and leakage increased slightly with ICD shortening, but the differences were not statistically significant (P .17).Peak and mean transvalvular pressure gradient were significantly reduced by ICD shortening (peak: control 26.75 4.33 mm Hg vs 22-mm ICD 23.85 2.91 mm Hg, P < .05;mean: control 17.57 3.59 mmHg vs 20-mm ICD 14.76 2.40 mm Hg, P .01).Aortic valve area was increased significantly by ICD shortening (control 2.03 0.37 cm 2 vs 18-mm ICD 2.71 0.47 cm 2 , P <.01).CONCLUSIONS With shortening of the ICD, the effect of increasing the aortic valve area and decreasing the pressure gradient was confirmed.Shortening the sinotubular junction diameter ( ICD) is important in aortic valvuloplasty for BAV.

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Publication Details

Journal
Annals of Thoracic Surgery Short Reports
Published
2025-09-01
DOI
https://doi.org/10.1016/j.atssr.2025.08.010
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Does Intercommissural Distance Shortening in Bicuspid Aortic Valve Repair Improve Valve Opening Area?

Yusei Okamoto, Satoshi Arimura, Satoshi Hoshino, Kiyotaka Iwasaki et al.
Annals of Thoracic Surgery Short Reports
Cardiac Valve Diseases and Treatments
article

Does Intercommissural Distance Shortening in Bicuspid Aortic Valve Repair Improve Valve Opening Area?

Yusei Okamoto, Satoshi Arimura, Satoshi Hoshino, Kiyotaka Iwasaki, Shiho Mineta, Júlio Yoshio Takada, Takashi Kunihara
article en

Abstract

BACKGROUND Standardized bicuspid aortic valve (BAV) repair makes 2 symmetrical cusps by plicating the fused cusp, which is accompanied by risk of aortic stenosis.Here, the effect of improving cusp mobility by shortening the intercommissural distance (ICD) on increasing the aortic valve area was examined in a BAV model using a pulsatile flow simulator.METHODS Six pairs of symmetrical BAV were created in a neo-Valsalva graft with bovine pericardium (free margin length, 26 mm; geometric height, 20 mm), which were incorporated into a pulsation circuit simulator.The ICD was gradually shortened, and the forward flow, leakage flow, pressure gradient, and aortic valve area were measured.The average value of a total of 18 measurements (3 for each model) was examined. RESULTSForward flow remained constant and leakage increased slightly with ICD shortening, but the differences were not statistically significant (P .17).Peak and mean transvalvular pressure gradient were significantly reduced by ICD shortening (peak: control 26.75 4.33 mm Hg vs 22-mm ICD 23.85 2.91 mm Hg, P < .05;mean: control 17.57 3.59 mmHg vs 20-mm ICD 14.76 2.40 mm Hg, P .01).Aortic valve area was increased significantly by ICD shortening (control 2.03 0.37 cm 2 vs 18-mm ICD 2.71 0.47 cm 2 , P <.01).CONCLUSIONS With shortening of the ICD, the effect of increasing the aortic valve area and decreasing the pressure gradient was confirmed.Shortening the sinotubular junction diameter ( ICD) is important in aortic valvuloplasty for BAV.

Annals of Thoracic Surgery Short ReportsVol. 4(1)
Jikei University School of Medicine (JP), Waseda University (JP)
Ministry of Health, Labour and Welfare, Japan Society for the Promotion of Science
Openalex Percentile: Top 64%
Cardiac Valve Diseases and Treatments
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