Central Nervous System Outcomes of Lazertinib Treatment in EGFR-Mutated Advanced NSCLC: Pooled Analysis From LASER201 and LASER301

In this pooled analysis of LASER201 and LASER301, lazertinib demonstrated a clinically meaningful treatment benefit and consistent safety profile in patients with EGFR-mutated advanced NSCLC and CNS metastases.

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Publication Details

Journal
Clinical Lung Cancer
Published
2025-09-01
DOI
https://doi.org/10.1016/j.cllc.2025.08.007
Citations
1
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
1.52

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article

Central Nervous System Outcomes of Lazertinib Treatment in EGFR-Mutated Advanced NSCLC: Pooled Analysis From LASER201 and LASER301

Joo-Hang Kim, Sergey Orlov, Ki Hyeong Lee, Yun‐Gyoo Lee et al.
1 citations
Clinical Lung Cancer
Lung Cancer Treatments and Mutations
1.52
article

Central Nervous System Outcomes of Lazertinib Treatment in EGFR-Mutated Advanced NSCLC: Pooled Analysis From LASER201 and LASER301

Joo-Hang Kim, Sergey Orlov, Ki Hyeong Lee, Yun‐Gyoo Lee, Yukyung Kim, Ji‐Youn Han, Yueh Ni Lim, H.B. Cho, Myung‐Ju Ahn, Mi Jung Kwon, James Chih‐Hsin Yang, Byoung Chul Cho, Chun Sen Lim, Youngjoo Lee, Hana Lee, Kyung-Hee Lee, Dong‐Wan Kim, Young Joo Min, Anastasia Zimina, Sung Sook Lee
article en
1 citations

Abstract

In this pooled analysis of LASER201 and LASER301, lazertinib demonstrated a clinically meaningful treatment benefit and consistent safety profile in patients with EGFR-mutated advanced NSCLC and CNS metastases.

Clinical Lung CancerVol. 26(8)
Ulsan College (KR), Yonsei University (KR), First Pavlov State Medical University of St. Petersburg (RU), Sarawak General Hospital (MY), Samsung Medical Center (KR), Seoul National University Hospital (KR), Sultan Ismail Specialist Hospital (MY), University of Ulsan (KR), National Cancer Center (US), Budgetary Health Care Institution of the Omsk Region "Clinical Oncology Center" (RU), Yuhan (South Korea) (KR), Inje University Haeundae Paik Hospital (KR), Kangbuk Samsung Hospital (KR), National Cancer Center (KR), National Taiwan University Hospital (TW), CHA University Bundang Medical Center (KR), Ulsan University Hospital (KR), CHA University (KR), Yeungnam University Medical Center (KR), Yonsei University Health System (KR), Chungbuk National University Hospital (KR), Sungkyunkwan University (KR)
Yuhan
Openalex Percentile: Top 15%
Lung Cancer Treatments and Mutations
1.52
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