Can fluoroquinolones be safely used in patients with immediate hypersensitivity reaction to penicillin?
Our study demonstrates a low positive rate (2.6%) for fluoroquinolone oral provocation testing among patients with penicillin allergy. These findings suggest that fluoroquinolones may be a viable and safe alternative in patients with a confirmed penicillin hypersensitivity and no history of multidrug allergy, and may be considered without prior provocation testing in selected cases.
Authors
- Murat Türk (ORCID: https://orcid.org/0000-0002-3290-2661)
- Elif Açar (ORCID: https://orcid.org/0000-0002-4669-5034)
- İnsu Yılmaz (ORCID: https://orcid.org/0000-0001-6023-6291)
- Serpil Köylüce (ORCID: https://orcid.org/0000-0002-6755-9074)
- Elif Aktaş Yapıcı (ORCID: https://orcid.org/0000-0002-8351-6330)
- Serhat Şeker (ORCID: https://orcid.org/0000-0002-2852-6181)
- Hatice Eylül Bozkurt Yılmaz (ORCID: https://orcid.org/0000-0001-7499-8676)
Institutions
- Erciyes University (TR)
Publication Details
- Journal
- Allergologia et Immunopathologia
- Published
- 2025-09-01
- DOI
- https://doi.org/10.15586/aei.v53i5.1443
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erciyes Üniversitesi